IL23/IL17-mediated Inflammation Induced by Aβ Accelerates Alzheimer's disease Development
نویسندگان
چکیده
منابع مشابه
Aβ-induced Golgi fragmentation in Alzheimer's disease enhances Aβ production.
Golgi fragmentation occurs in neurons of patients with Alzheimer's disease (AD), but the underlying molecular mechanism causing the defects and the subsequent effects on disease development remain unknown. In this study, we examined the Golgi structure in APPswe/PS1E9 transgenic mouse and tissue culture models. Our results show that accumulation of amyloid beta peptides (Aβ) leads to Golgi frag...
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ژورنال
عنوان ژورنال: Frontiers in Human Neuroscience
سال: 2015
ISSN: 1662-5161
DOI: 10.3389/conf.fnhum.2015.217.00345